Seeing Clearly at 50: How NMN and Resveratrol Changed My Eyesight
About a year ago, I found myself in a frustrating place. At 50, my vision had deteriorated to the point where I couldn’t read menus or see the text on my phone without glasses. I started wearing them reluctantly, assuming it was just another symptom of aging I had to accept.
But I wasn’t ready to give in.
Around that time, I began a broader fitness campaign—an overhaul of how I treated my body and health. Part of that journey led me to NMN (Nicotinamide Mononucleotide). After reading up on its potential benefits, I went all in: I bought a kilo of NMN and started taking about a gram daily.
Six months later, I realized something remarkable: my vision had improved significantly. I no longer needed glasses for daily tasks. I could read fine print again. At 50 years old, this felt nothing short of miraculous.
Naturally, I wanted to understand what was happening. That’s when I dove into the research. Animal studies have shown that NMN can protect and even rescue photoreceptor cells in the retina, particularly in mice genetically lacking the NAMPT enzyme critical for NAD+ production. NMN injections restored retinal structure and function even in models of light-induced damage and diabetic retinopathy.
Other mouse studies revealed NMN’s ability to protect against oxidative stress and inflammation after retinal detachment, preserving retinal layers and boosting antioxidant defenses via the NAD+/SIRT1 pathway. Scientific reviews consistently show that NAD+ levels decline in the aging eye, and boosting them with NMN may help protect against neurodegeneration.
Of course, all this is preclinical. There are no robust human trials yet proving NMN’s vision benefits. But my personal experience mirrored these findings.
Later, I added Resveratrol to the mix. As a natural polyphenol, it supports the activation of SIRT1—an important protein in the NAD+ pathway. The combination of NMN and Resveratrol supercharged my progress. My energy levels increased, recovery after workouts improved, and my motivation to train went through the roof. Most importantly, my eyesight remained sharp.
Resveratrol also shows impressive preclinical data in protecting retinal pigment epithelial cells and retinal ganglion cells from oxidative stress, inflammation, and apoptosis. It even shows promise in models of glaucoma, inherited retinal degeneration, and proliferative vitreoretinopathy. Again, this is mostly in rodents and cell cultures, but the mechanisms align: SIRT1 activation, reduced oxidative damage, and enhanced cellular resilience.
I can’t claim NMN and Resveratrol are miracle cures for everyone. But I can say this: they changed my life.
I went from squinting at screens and depending on glasses to living with clear vision and renewed vitality. That’s not just science—that’s my story.
Author: Mark H